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Laboratory diagnostics
Detection of marker germs
Certain germs/bacteria are particularly destructive to the periodontal tissues and bone. This detection test the presence of bacteria that can cause periodontitis (gum inflammation) and periimplantitis (inflammation around an implant). Any supplemental drug treatment can be tested for effectiveness.
This painless test involves using a paper tip to carefully take a sample from the gingival pocket.

Genetic testing for inflammatory factors
Certain variants of the gene for the inflammatory factors Interleukin-1, Interleukin-6 and even TNF-α increase the risk of a chronic aggressive periodontitis. About 15 to 20 percent of the population carry this variant, which leads to an increased tendency to inflammation.
The gene test determines whether you are a carrier of this gene variant from a cheek swab or blood cells. Today’s methods permit graduation from 0 to 4.
We can determine your individual tendency to inflammation with this method and set down, amongst other things, the ideal time interval for regular professional teeth cleaning to prevent periodontal disease.

Chewing gum saliva test
A chewing gum saliva test can be used to determine the abrasion of heavy metal sources in the mouth that takes place during everyday chewing. For this test, saliva is collected over 10 minutes of gum chewing. A multi-element analysis (MEA) is then used to identify which common dentistry materials are present, if any.

Lymphocyte Transformation Test (LTT)
In allergology, the LTT has proven successful for diagnosing individual allergic sensitisations. Compared to earlier variants, it is today deemed specific and sensitive. It can be used to examine metals, synthetic materials, as well as many other denture materials safely, and in comparison to the skin test, without stress for the patient. With the LTT you can only show the immunereaction caused by the foreign material but not if the immunereaction has a harmfull nature.

Basophile Degranulation Test (BDT)
Immediate-type, Type Iallergies can be shown in vitro with the CAST_test (Basophile Degranulation Test or leucotrien-release test). This type of allergy occurs seldom with synthetic materials (acrylates). We do not find it with metals which react only Type IV

Immune Tolerance Test (ITT)
The Immune Tolerance Test (ITT) allows conclusions about current stress through a specific allergen. The ITT Immunotolerance test with the measurement of the induction of a specific pattern of citokines induced by foreign materials gives us the possibility to show the clinical significance of the immunesystem reaction. We can find alongside proinflammatory, clinically relevant immunersystemreactions also clinically mute sensitations

Individual intolerance to titanium
Titanium intolerance is not a classic allergy. It frequently occurs through abrasion particles of the titanium surface. The result is a strong inflammatory reaction which clinically has all the signs of an allergic reaction (pseudoallergy). Persons who have a genetic disposition to severe inflammatory reaction have a higher risk.About 15% of the European population shows such an excessive inflammatory response. The inflammatory disposition can be seen by a functional test called Monocheck or by a genetic testing of the inflammatory diposition. The Titanium hypersensitivity can be tested best by the ITT-cytokine test (Immunotolerance test). This was shown recently by an evaluation done by the Robert Koch Institut Germany.

Inflammatory factors in saliva
Inflammatory processes in the oral cavity can be detected using a saliva test for two substances: putrescine and cadaverine. Both substances have an impact on blood pressure and are toxic in higher concentrations.
For the test, 10 ml of morning saliva is collected in a special tube immediately after waking.

OroTox test
The OroTox test is used to determine the amount of decay products in the gum pockets, some of which may be carcinogenic.

Urine tests for citrullin
This laboratory test provides information about the formation rate of nitric oxide and other nitrogen derivates (Peroxynitrit) . Citrulline is measured in the patient's first morning urine after waking.

S-100 protein detection
The s-100 protein detection test was originally developed as way to control and monitor the treatment of malignant melanoma.
This test can also detect damage to the blood-brain barrier (increased permeability). It involves measuring the amount of s-100 protein in venous blood.

ATP evidence in cells
The best marker to prove mitochondrial damage (e.g. with chronic inflammatory conditions) is the ATP. ATP is the decisive energy supplier for our cells. Malfunctions of numerous metabolic processes are the result of low ATP levels.

Household dust analysis
Your living space may be contaminated with allergenic substances (allergens) or toxins that are detrimental to your health. A basic household dust screening can reveal problems caused by the following factors:

- Insecticides
- Fungicides
- Flame retardants
- Emollients
- Polycyclic aromatic hydrocarbons
- Benzo(a)pyrenes
- Molds and mold spores
- Formaldehyde